Journal of Gastrointestinal Infections

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VOLUME 3 , ISSUE 1 ( 2013 ) > List of Articles


Profile and outcome of liver diseases in pregnancy -Ahospital based study

Deepinder Kaur, Rajoo Singh Chhina, Ashima Kaura, Vishal *, H. S. Pannu, Amandee *

Keywords : Hepatitis, Liver disease, Maternal mortality

Citation Information : Kaur D, Chhina RS, Kaura A, * V, Pannu HS, * A. Profile and outcome of liver diseases in pregnancy -Ahospital based study. J Gastrointest Infect 2013; 3 (1):41-44.

DOI: 10.5005/jogi-3-1-41

License: CC BY-SA 4.0

Published Online: 01-07-2013

Copyright Statement:  Copyright © 2013; The Author(s).


Background & Objective: Liver disease in pregnancy can have serious consequences. We studied the profile of liver disease in pregnant women and its correlation with outcome of pregnancy during the hospital stay in a tertiary care hospital. Methods: Pregnantwomen with liver disease admitted in the departments of Medicine, Gastroenterology and Obstetrics & Gynaecology between January 2011 and June 2012 in a tertiary care hospital of North India were evaluated for various parameters. Results: Out of 2663 pregnant women, 92 patients (3.45%) were diagnosed to have liver disease. Acute viral hepatitis (AVH) was found in 42 (45.6%) and pregnancy specific liver disease in 39 (42.4%) patients. Hypertensive disorder of pregnancy including HELLP Syndrome (Hemolysis, Elevated liver enzymes, Low platelet count) was seen in 27 patients (29.3%). Four patients had leptospirosis and hepatitis E co-infection. Overallmaternal and perinatal mortality was 7.6% (7/92) and 25% (23/92) respectively. Interpretation and Conclusion: Acute viral hepatitis (45.6%) was the most common cause of liver disease in pregnancy in our study.

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