Journal of Gastrointestinal Infections

Register      Login

VOLUME 4 , ISSUE 1 ( 2014 ) > List of Articles

REVIEW ARTICLE

Association of Reactive Arthritis with Enteric Pathogens

Varsha Gupta

Citation Information : Gupta V. Association of Reactive Arthritis with Enteric Pathogens. J Gastrointest Infect 2014; 4 (1):16-18.

DOI: 10.5005/jogi-4-1-16

License: CC BY-SA 4.0

Published Online: 01-10-2015

Copyright Statement:  Copyright © 2014; The Author(s).


Abstract

Reactive arthritis (ReA) also known as post infectious arthritis, affects 1-4% of people days to weeks after being infected by an enteric, urogenital or upper respiratory infection. The most common enteric bacterial pathogens that have been associated with ReA include Salmonella, Shigella, Campylobacter, enterotoxigenic Escherichia coli and Yersinia. It is quite necessary to determine the burden of ReA due to enteric infections using standard criteria. The clinician should investigate for the evidence of previous bacterial infections. In addition, it is very important to carry follow-up studies of patients with enteric infection so as to clarify the association of ReA with enteric pathogens. No curative treatment for reactive arthritis (ReA) exists. Instead, treatment aims at relieving symptoms and is based on symptom severity. Prevention of enteric and genitourinary bacterial infections is the best option.


PDF Share
  1. Townes JM. Reactive arthritis after enteric infections in the United States: the problem of definition. Clin Infect Dis 2010;50:247-54.
  2. Carter JD, Hudson AP. Reactive arthritis: clinical aspects and medical management. Rheum Dis Clin North Am 2009;35:21- 44.
  3. Wu IB, Schwartz RA. Reiter's syndrome: the classic triad and more. J Am Acad Dermatol 2008;59:113-21.
  4. Penn H, Keat A. Post-infective arthritis. Medicine 2006;34: 413-6.
  5. Locht H, Krogfelt KA. Comparison of rheumatological and gastrointestinal symptoms after infection with Campylobacter jejuni/coli and enterotoxigenic Escherichia coli. Ann Rheum Dis 2002;61:448-52.
  6. Hannu T, Mattila L, Nuorti JP, Ruutu P, Mikkola J, Siitonen A, et al. Reactive arthritis after an outbreak of Yersinia pseudotuberculosis serotype O:3 infection. Ann Rheum Dis 2003;62:866-9.
  7. Eapen B. A new insight into the pathogenesis of Reiter's syndrome using bioinformatics tools. International J Dermatol 2003:42,242-3.
  8. Inman RD, Johnston MEA, Hodge M, Falk J, Helewa A. Post dysenteric reactive arthritis. Arthritis Rheum 1988;31:1377-83.
  9. Hannu T, Mattila L, Siitonen A, Leirisalo RM. Reactive arthritis attributable to Shigella infection: a clinical and epidemiological nationwide study. Ann Rheum Dis. 2005;64:594-8.
  10. Hill Gaston JS, Lillicrap MS. Arthritis associated with enteric infection. Best Pract Res Clin Rheumatol 2003;17:219-39.
  11. McColl GJ, Diviney MB, Holdsworth RF. HLA-B27 expression and reactive arthritis susceptibility in two patient cohorts infected with Salmonella Typhimurium. Aust NZJ Med 2000;30:28-32.
  12. Singh M, Ganguli NK, Singh H, Deodhar SD, Sethi S, Sharma M. Role of 30 kDa antigen of enteric bacterial pathogens as a possible arthritogenic factor in post-dysenteric reactive arthritis. Indian J Pathol Microbiol. 2013;56:231-7.
  13. Sieper J, Rudwaleit M, Braun J, Heijde VD. Diagnosing reactive arthritis: role of clinical setting in the value of serologic and microbiologic assays. Arthritis Rheum 2002;46:319-27.
  14. Carter JD. Reactive arthritis: defined etiologies, emerging pathophysiology and unresolved treatment. Infect Dis Clin North Am 2006;20:827-47.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.