Journal of Gastrointestinal Infections

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VOLUME 4 , ISSUE 1 ( 2014 ) > List of Articles


Trends of Hepatitis A & E Infection in a Tertiary Care Hospital of North India

Deepinder Kaur, Veenu Gupta, Rajoo Singh Chhina, Jyoti Chaudhary, Manisha Aggarwal, Kanwaldeep Lyall

Citation Information : Kaur D, Gupta V, Chhina RS, Chaudhary J, Aggarwal M, Lyall K. Trends of Hepatitis A & E Infection in a Tertiary Care Hospital of North India. J Gastrointest Infect 2014; 4 (1):44-46.

DOI: 10.5005/jogi-4-1-44

License: CC BY-SA 4.0

Published Online: 01-10-2015

Copyright Statement:  Copyright © 2014; The Author(s).


Background & Objectives: Acute viral hepatitis (AVH) is a systemic infection affecting the liver predominantly. It is a major public health problem in India and other developing nations having inadequate sanitary conditions. This study was undertaken to determine the trends of Hepatitis A & E & their coinfection in a tertiary care hospital so that appropriate management of cases as well as prevention can be planned. Material & Methods: Over a 2-year period, a total of 5894 serum samples were collected from clinically suspected cases of hepatitis. The serum samples were screened for IgM anti-HAV and IgM anti-HEV. Seasonal variation & age group wise seropositivity of hepatitis A & E was studied. Results: Out of the total 5894 samples screened, the percentage positivity of Hepatitis A was 6.7%, 6.2% and Hepatits E was 14.1%, 13.9% respectively in 2012 & 2013. Of both Hepatitis A & E positive cases, males outnumbered females. Majority of HAV positive cases were children whereas majority of hepatitis E positive cases were adults. Interpretation & Conclusion: The prevalence of HEVwas more than HAVin enterally transmitted viruses, making them a major public health problem in our area. Seasonal trends of infection were observed in addition, co-infection though infrequent, but still detected in many cases.

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