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VOLUME 2 , ISSUE 1 ( 2012 ) > List of Articles

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Sensitivity pattern of Salmonella serotypes from a tertiary care hospital of Punjab

Kanwaldeep Singh, Rajoo S Chhina, Rama Gupta, Amarjeet Kaur, Deepinder Kaur, Pooja Suri

Keywords : Antimicrobial sensitivity, Enteric fever, Salmonella Paratyphi A, Salmonella Typhi

Citation Information : Singh K, Chhina RS, Gupta R, Kaur A, Kaur D, Suri P. Sensitivity pattern of Salmonella serotypes from a tertiary care hospital of Punjab. J Gastrointest Infect 2012; 2 (1):59-61.

DOI: 10.5005/jogi-2-1-59

License: CC BY-SA 4.0

Published Online: 01-09-2015

Copyright Statement:  Copyright © 2012; The Author(s).


Abstract

Enteric fever is classically caused by S. Typhi & S. Paratyphi A, B & C and it is known to be endemic in India. For optimal patient care, precise information on antibiotic susceptibility pattern is required. Hence, this studywas undertaken to know the antimicrobial sensitivity profile of Salmonella serotypes isolated fromblood in a tertiary care hospital of Punjab. All the blood samples received from January 2010 – December 2011 were processed by automated blood culture systems (BACTEC 9240/Bac T-Alert 3D). Identification and antimicrobial susceptibility pattern of Salmonella strains was studied by automated identification system (Micro Scan Walk-Away/ VITEK 2). Out of a total of 35854 blood samples, 5234 (14.6%) samples were found to be positive for bacterial growth, of which 363 (6.93%) were Salmonella spp. Of these, 281 (77.4%) were S. Typhi and 82 (22.6%) were S. Paratyphi A. Only 2 (0.7%) isolates of S. Typhi were found resistant to ampicillin and trimethoprim-sulfamethoxazole, and 5 (1.8%) were resistant to ciprofloxacin & levofloxacin. All the S. Typhi isolates were sensitive to 3rd generation cephalosporins. S. Paratyphi A isolateswere sensitive (100%) to all the drugs, except trimethoprim-sulphamethoxazole (97.6%) & ceftriaxone (98.8%). Though multi drug resistant Salmonella are being reported fromvarious parts of India, in our region the Salmonella isolates are still susceptible to the commonly used drugs.


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  1. Gautam V, Gupta NK, Cahudhary U, Arora DR Sensitivity Pattern of Salmonella serotypes in Northern India. Brazilian J Infect Dis 2002;6:281-7.
  2. Woodward TE, Smadel JE, Ley HL, Green R. Preliminary report on beneficial effects of chlormycetin in treatment of typhoid fever. Ann Int Med 1948;29:131-4.
  3. Mirza SH, Beeching NJ, Hart CA. Multi-drug resistant typhoid: A global problem. J Med Microbiol 1996;44:317-9.
  4. Gupta V, Kaur J, Chander J. An increase in enteric fever cases due to Salmonella Paratyphi Ain & around Chandigarh. Indian J Med Res 2009;129(1)95-8.
  5. Tankhiwale SS, Agrawal G, Jalgaonkar SV. An unusually high occurrence of Salmonella enterica serotype paratyphi A in patients with enteric fever. Indian J Med Res 2003;117:10-2.
  6. Yashavanth R, Vidyalakshmi K. The re-emergence of chloramphenicol sensitivity among enteric fever pathogens in Mangalore. J Clin Diagn Res 2010;(4);3106-8.
  7. Verma S, Thakur S, Kanga A, Singh G, Gupta P. Emerging Salmonella Paratyphi A enteric fever and changing trends in antimicrobial resistance pattern of Salmonella in Shimla. Indian J Med Microbiol 2010;28(1):51-3.
  8. Prajapati B, Rai GK, Rai SK, Upreti HC, Thapa M, Singh G, et al. Prevalence of Salmonella typhi and paratyphi infection in children: a hospital based study. Nepal Med Coll J 2008; 10(4): 238-41.
  9. Lakshmi V, Ashok R, Susmita J, Shailaja VV. Changing trends in the antibiograms of Salmonella isolates at a tertiary care hospital in Hyderabad. Indian J Med Microbiol 2006;24(1):45-8.
  10. Sen B, Dutta S, Sur D, Manna B, Deb AK, Bhattacharya SK, et al. Phage typing, biotyping & antimicrobial resistance profile of Salmonella enterica serotype Typhi from Kolkata. Indian J Med Res 2007;125(5):685-8.
  11. Mathura KC, Chaudhary D, Simkhada R, Pradhan M, Shrestha P, Gurubacharya DL. Study of clinical profile and antibiotic sensitivity pattern in culture positive typhoid fever cases. Kathmandu Univ Med J 2005;3(4):376-9.
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