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VOLUME 8 , ISSUE 1 ( December, 2018 ) > List of Articles

Research News Scan

Evolution-proof Antibiotics

Anshul Sood

Keywords : Antimicrobial resistance, Evolution-proof antibiotics, Horizontal gene transfer

Citation Information : Sood A. Evolution-proof Antibiotics. J Gastrointest Infect 2018; 8 (1):51-51.

DOI: 10.5005/jp-journals-10068-0022

License: CC BY-NC 4.0

Published Online: 01-12-2018

Copyright Statement:  Copyright © 2018; The Author(s).


Abstract

Evolving resistance in pathogenic bacteria has compromised the efficacy of current antibiotics. The need of the hour dictates producing antibiotics to which the bacteria cannot produce resistance. Attractive options possible are first, formulating ‘evolution-proof’ antibiotics via mutation or horizontal gene transfer which bacteria cannot resist and secondly by producing compounds to which resistance may develop, but rarely at a rate that can make it become epidemic.

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