Journal of Gastrointestinal Infections

Register      Login

VOLUME 11 , ISSUE 1 ( January-December, 2021 ) > List of Articles


Shigella flexneri Sepsis in a Well-nourished Immunocompetent Child: A Rare Case Report

Rama Gupta, Veenu Gupta, Deepak Bhat, Reetu Goyal, Jyoti Chaudhary, Menal Gupta

Keywords : Bacteremia, Intravenous antibiotics, Shigella flexneri, Stool culture, Well-nourished child

Citation Information : Gupta R, Gupta V, Bhat D, Goyal R, Chaudhary J, Gupta M. Shigella flexneri Sepsis in a Well-nourished Immunocompetent Child: A Rare Case Report. J Gastrointest Infect 2021; 11 (1):44-46.

DOI: 10.5005/jp-journals-10068-3046

License: CC BY-NC 4.0

Published Online: 18-01-2022

Copyright Statement:  Copyright © 2021; The Author(s).


Shigella infections are usually restricted to the intestine. There are a few reports of Shigella isolated from the blood and most of these are from children, usually the neonates and the malnourished. In the small number of adult cases of Shigella bacteremia which have been reported, there appears to be an association with underlying disease and immunosuppression including acquired immunodeficiency syndrome. We report a rare case of septicemia with Shigella flexneri in a well-nourished, obese child, with no other predisposing underlying condition. With the prompt and aggressive symptomatic treatment along with administration of appropriate antibiotics based upon the antimicrobial susceptibility pattern of the isolate, the patient's recovery was uneventful.

  1. Levine MM, Kotloff KL, Barry EM, et al. Clinical trials of Shigella vaccines: two steps forward and one step back on a long, hard road. Nat Rev Microbiol 2007;5(7):540–553. DOI: 10.1038/nrmicro1662.
  2. Niyogi SK. Shigellosis. J Microbiol 2005;43(2):133–143. PMID: 15880088.
  3. Erqou SA, Teferra E, Mulu A, et al. A case of shigellosis with intractable septic shock and convulsions. Jpn J Infect Dis 2007;60(5):314. PMID: 17881877.
  4. Goldberg M, Calderwood SB, Edwards MS, et al. Shigella infection: epidemiology, microbiology, and pathogenesis. Recuperado el 2013;14:4–130.
  5. Jain S, Sharma M, Gupta R, et al. Multidrug resistant Shigella flexneri: a rare case of septicaemia in an infant. J Clin Diagn Res 2014;8(6):03–04. DOI: 10.7860/JCDR/2014/8434.4511.
  6. Kamble R. Bacteraemia due to Shigella flexneri in an adult. Int J Curr Microbiol App Sci 2015;4(4):870–873. Available from:
  7. Jauhari S, Nautiyal S, Singh S. Septicaemic invasion by Shigella flexneri. Sch J Med Case Rep 2017;5(7):434–435. DOI: 10.21276/sjmcr.
  8. Sebhat AE, Endale T, Andargachew M, et al. A case of shigellosis with intractable septic shock and convulsions. Jpn J Infect Dis 2007;60(5):314–317. PMID: 17881877.
  9. Lakxmikant C. Shigellosis with septicemia. J Assoc Phys India 1982;30:841. PMID: 7185828.
  10. Yen JB, Chang KW, Wu TL, et al. Shigella flexneri sepsis in an Infant. Chang Gung Med J 2003;26(8):611–614. PMID: 14609044.
  11. Saraswathi K, Anuradha DE, Jog A, et al. Shigella septicemia. Indian Pediatr 2002;39(8):777–779. PMID: 12196693.
  12. Sharma S, Arora A. Shigella flexneri bacteremia in an adults. J Lab Physicians 2012;4(1):65–66. DOI: 10.4103/0974-2727.98682.
  13. Kraybill EN, Controni G. Septicemia and enterocolitis due to Shigella sonnei in a newborn infant. Pediatrics 1968;42(3):529–31. PMID: 4877932.
  14. Delgado M, Saenz C, Glasman P, et al. Shigella flexneri bacteremia in children: two case report and review of literature. Rev Chilena Infectol 2018;35(3):317–320. DOI: 10.4067/s0716-10182018000300317.
  15. Ashkenazi S. Shigella infections: treatment and prevention in children. UpToDate 2014. Available from: http://www. uptodate. com/contents/shigella infection-treatment and prevention-in-children.
  16. Goren A, Freier S, Passwell JH. Lethal toxic encephalopathy due to childhood shigellosis in a developed country. Pediatrics 1992;89(6):1189–1193. PMID: 1594376.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.