This chapter discusses laparoscopic management of pelvic organ prolapse, where genital prolapse is a common pathology. Many surgical techniques are used to treat female genital prolapse, and this is in itself proof of how difficult it is to deal with this problem. The surgical technique in current use is laparoscopic mesh promontofixation of the cervix in case of supracervical hysterectomy, of the uterus when this is conserved, or of the vaginal vault in case of posthysterectomy vault prolapse. The standard method was to leave the uterus in place in order to avoid opening the vagina and the consequent risks of infection involving the prosthesis. If the uterus is conserved, a passage must be prepared through the broad ligament for the two arms of the prosthesis. Laparoscopy appears to be a feasible approach for surgical correction. The colposuspension and paravaginal repair phase is completed by peritonization using a running suture of resorbable monofilament material.