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Chapter-18 Erythema Multiforme

BOOK TITLE: Essential of Dermatology, Venereology and Leprosy

Author
1. Chattopadhyay SP
ISBN
9788180610172
DOI
10.5005/jp/books/11611_18
Edition
1/e
Publishing Year
2003
Pages
2
Author Affiliations
1. Armed Forces Medical College Pune, Vivekananda Institute of Medical Sciences, Ramakrishna Mission Seva Pratishthan; Calcutta Medical and Research Institute, Kolkata, West Bengal, India
Chapter keywords
Reaction pattern, Skin and mucous membrane involvement, Stevens Johnson syndrome, Treatment: Oral /JV cortico steroids < antibiotics rarely.

Abstract

Is a reaction pattern of skin and mucous membrane too many different stimuli characterized by presence of erythematous maculopapular, of vesicles and or bullae? Aetiology: Immunological mechanism with immune complexes as basic aetiological factors. Etiologic factors of erythema multiforme. Viral infection, bacterial infection, drugs, connective tissue disorders, pregnancy, contact enzyme. Clinical feature: Maculopapular. Vesiculobullous form: Severe Bullous form (Stevens Johnson Syndrome) mucous membrane involvement, eyes severe catarrhal or purulent nctivitis present. Skin lesions they are variable range between vesicle, bullae, bullies and pustules. Constitutional systems: Respiratory, renal, and GIT involvement is known. Treatment: For mild and intermediate forms, only symptomatic treatment in the form of local bland application PP baths. Severe form: Corticosteroids are required to control severe systemic manifestations, 0.5-1 mg/kg body weight for 3 to 4 weeks. General treatment: Good diet, daily bath with PP solution.

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