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Chapter-22 Acute Proliferative Glomerulonephritis and Crescentic Glomerulonephritis

BOOK TITLE: Principles and Practice of Pediatric Nephrology

Author
1. Vijayakumar M
2. Nammalwar BR
ISBN
9788180613043
DOI
10.5005/jp/books/11074_22
Edition
1/e
Publishing Year
2004
Pages
10
Author Affiliations
1. Kanchi Kamakoti CHILDS Trust Hospital, Chennai, Tamil Nadu, India, Government Medical College, Manjeri, Kerala, India, Pediatric Kidney Foundation, Chennai, Dr Mehta’s Hospitals Pvt Ltd., Chennai, Government Medical College, Kozhikode, Kerala, India, Mehta Children’s Hospital, Chetpet, Chennai, Tamil Nadu, India, Government Medical College, Kozhikode, Kerela, India, Mehta Children’s Hospital, Chennai, Tamil Nadu, Mehta’s Children Hospital, Chennai, Tamil Nadu, India, Mehta Children’s Hospital, Chennai, Tamil Nadu, India, Dr. Mehta’s Hospital; Chennai Pediatric Kidney Foundation, Chennai, India, Chennai Pediatric Kidney Foundation, Dr Mehta’s Hospitals Pvt. Ltd, Chennai, National Botanical Research Institute, Lucknow-226 001, India, Medical College, Alappey, Kerala, Manipal Institute of Nephrology and Urology, Manipal Hospital, Bangalore, Karnataka, India, Kanchi Kamakoti, Childs Trust Hospital, Chennai
2. Kanchi Kamakoti CHILDS Trust Hospital, Chennai, Tamil Nadu, India, Kanchi Kamakoti CHILDS, Trust Hospital, Chennai, Kanchi Kamakoti CHILDS Trust Hospital, Chennai, India, Institute of Child Health, Hospital for Children; Mehta Children Hospital, Chennai, Tamil Nadu, Mehta Children’s Hospital, Chennai, Tamil Nadu, India, Kanchi Kamakoti CHILDS Trust Hospital, Chennai, Mehta's Multispeciality Hospital, Chennai, Tamil Nadu, India, Institute of Child Health, Hospital for Children and Dr Mehta’s Children’s Hospital, Chennai, Tamil Nadu
Chapter keywords

Abstract

Acute proliferative glomerulonephritis (acute proliferative GN) is basically a histological diagnosis. Acute nephritic syndrome (ANS) is a clinical syndrome associated with acute proliferative glomerulonephritis. ANS consists of hematuria, proteinuria, oliguria and volume overload with or without azotemia. ANS and acute proliferative glomerulonephritis are used synonymously. Acute proliferative glomerulonephritis is used to describe a clinico-pathological syndrome characterized by sudden onset of hematuria, proteinuria and red cell casts and is accompanied by hypertension, edema and impaired renal function. The histology is in the form of endocapillary and mesangial hypercellularity associated with polymorphonuclear cell invasion. The nephritogenic M types causing acute proliferative glomerulonephritis include M types 1, 3, 4, 12, 25, 49 in pharyngitis and 2, 49, 55, 57, 60 in pyoderma, the two common infections associated with post-streptococcal glomerulonephritis.

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