The anatomical and physiological changes in pregnancy are associated with what are perceived by many women as minor disorders or ‘nuisance’ problems of pregnancy. Nausea and vomiting are very common problems of early pregnancy and can result in the first trimester being viewed as a miserable time. The precise etiology is unknown but it may be a response to rising estrogen and/or very high hCG levels as it is more common in multiple pregnancy or with a molar pregnancy. Psychological factors may also have a role through their direct action on the emetic center in the midbrain. Symptoms tend to recur in a quarter of women in a subsequent pregnancy. If the vomiting is precipitated by reflux then the use of alginates or antacids may help. There is reluctance from patients to take medication in pregnancy but these patients may benefit from an antiemetic agent such prochloperazine, cyclizie or metoclopramide. Heartburn is a common problem in pregnancy mediated by relaxation of the physiological sphincters of the stomach due to elevated progesterone levels. The resulting reflux of the acid gastric contents and bile irritates the lower esophagus and may also contribute to nausea and vomiting. Carpal tunnel syndrome refers to the tingling sensation experienced in the distribution of the median nerve in the hand and in some cases radiating up the forearm. Constipation is one of the most common problems encountered in pregnancy and it is due to the smooth muscle relaxant effect of progesterone. Urinary frequency is encountered from early on in pregnancy secondary to hyperdynamic circulation and supranormal urine production by the kidneys. Progesterone can result in relaxation of the pubic symphysis joint and the surrounding ligaments as the pregnancy progresses. Hemorrhoids can be troublesome and aggravated by pregnancy associated constipation. The main contributory factor for the development of varicosities is a degree of pelvic venous obstruction due to pelvic pressure exerted by the growing uterus. Varicose veins in the legs can be disfiguring and painful.