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Chapter-34 Induction of Labor

BOOK TITLE: Essentials of Obstetrics

Author
1. Arulkumaran Sabaratnam
2. Mukhopadhyay Sambit
ISBN
9788180613623
DOI
10.5005/jp/books/10288_34
Edition
1/e
Publishing Year
2004
Pages
9
Author Affiliations
1. St. George’s Hospital Medical School London, St. George’s Hospital Medical School, London, St George’s Hospital Medical School, London, United Kingdom, St George’s Hospital Medical School, London, United Kingdom, e-mail: sarulkum@sghms.ac.uk, St George s University of London, London, UK, St George’s Hospital Medical School Cranmer Terrace, London SW17 0RE, United Kingdom, St George’s University of London, Cranmer Terrace, London, United Kingdom, FIGO; University of Nicosia, Nicosia, Cyprus
2. Norfolk and Norwich University Hospital NHS Trust, Norwich, United Kingdom, NRS Medical College and Hospital, Kolkata), Salt Lake City, Kolkata, India, Norfolk and Norwich University Hospital, NHS Trust, Norwich, United Kingdom
Chapter keywords
uterine contractions, pregnant woman, labor, vaginal delivery, fetus, period of gestation, ultrasound, early second trimester, structural and biochemical changes, cervix, sphincteric organ, intravenous oxytocin, buccal oxytocin, cervical ripening, oxytocin administration, cervical change, fetal descent, uterine hyperstimulation, delivery systems, titration of oxytocin, augmented labor, fetal hypoxia, water retention, antidiuretic action, membranes, cord prolapse, intrauterine infection, intrauterine fetal death (IUFD), pregnancy, coagulation tests, fibrinogen, fibrinogen degradation products, platelet count

Abstract

Induction is the initiation of uterine contractions in a pregnant woman who is not in labor with the intention of achieving vaginal delivery. Induction is indicated when the risk of continuation of pregnancy exceeds the risk associated with induction and delivery. A thorough evaluation of mother and fetus is required before labor is induced. Confirmation of the period of gestation is required and ideally this should have been with the use of ultrasound in the first or early second trimester. Important structural and biochemical changes take place in the cervix thereby transforming the cervix from a sphincteric organ acting to preserve and contain the growing fetus to a canal which softens, shortens and dilates to facilitate the passage of the fetus. Regular uterine contractions achieved with intravenous oxytocin or buccal oxytocin would result in cervical ripening in many cases. The goal of oxytocin administration is to effect uterine activity that is sufficient to produce cervical change and fetal descent while avoiding uterine hyperstimulation. Various delivery systems have been used for titration of oxytocin during induced or augmented labor. Apart from the risk of fetal hypoxia secondary to uterine hyperstimulation, oxytocin can cause water retention due to its antidiuretic action. When the membranes have ruptured spontaneously before the onset of labor there is a risk of cord prolapse, intrauterine infection and increased operative deliveries with induction of labor. Intrauterine fetal death (IUFD) at any stage of pregnancy is a tragic event. Expensive coagulation tests like estimation of fibrinogen, fibrinogen degradation products are often not necessary but platelet count should be checked before any intervention is planned.

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