This chapter discusses tumours of oropharynx, which may be benign tumours or malignant tumours. Benign tumours are such as papilloma, adenoma or pleomorphic adenoma of epithelial origin. Benign tumours also may be fibroma, lipoma, haemangioma, neurinoma or chondroma of connective tissue origin. Malignant tumours, most commonly seen are malignancy of the tonsil, base of tongue or wall of pharynx. Most of alignant tumours are squamous cell carcinoma, while the rest may be adenocarcinoma and adenocystic carcinoma or lymphomas. Lymphatic drainage of oropharynx occurs to jugulodigastric group of lymph nodes which is a part of upper deep cervical group of lymph nodes. Papilloma is usually pedunculated and occurs in oral cavity, tonsil, soft palate and faucial pillars. Pleomorphic adenoma is a potentially malignant benign neoplasia and requires total surgical excision. Squamous cell carcinoma is the most common neoplasm, which may be well differentiated, moderately differentiated or poorly differentiated.