The onset of puberty is an evolving sequence of maturational steps. The hypothalamic pituitary gonadal system differentiates and functions during fetal life and early infancy. Thereafter, it is suppressed to low activity levels during childhood by a combination of hypersen­sitivity of the “gonadostat” to estrogen, negative feedback and an intrinsic CNS inhibitor. At the onset of puberty, GnRH secretion is restored. In many societies throughout history, puberty has been a time of celebration. Puberty has been defined as the state of being functionally capable of procreation. The cascade of events initiated by the release of pulsatile gonadotropin releasing hormone (GnRH) from prepubertal feedback and central negative inhibition results in increased levels of gonadotropins and steroids with appearance of secondary sexual characteristics and eventual adult function (menarche and, later ovulation). Adolescence is the span of human growth extending from the immaturity of childhood to the physical and psychological maturity of adulthood. This period extends from 10 to 20 years (WHO, 1977). Puberty marks the beginning of adolescence. During puberty, the secondary sexual characteristics appear and mature, the adolescent growth spurt takes place, fertility is attained, and significant physical, psychological, and behavioral changes occur, transforming the child into an adult.