This chapter discusses the general features of cutaneous circulation. This chapter also describes the special features of cutaneous circulation, namely—white reaction, occurring when the pointed object is drawn lightly over the skin, with the mechanical stimulus causing contraction of pre-capillary sphincters and draining out of blood from capillaries and small veins and Triple response, a combination of three phenomena appearing with the stroking of skin more firmly, i.e. Red reaction, Wheal and Flare. The Axon reflex, a unique example of antidromic conduction and Reactive hyperaemia, an increase in blood flow after a brief period of occlusion are also highlighted.