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Chapter-23 Congenitally Corrected Transposition of Great Arteries

BOOK TITLE: Clinical Diagnosis of Congenital Heart Disease

Author
1. Manojkumar Rohit
ISBN
9788184481617
DOI
10.5005/jp/books/10126_23
Edition
1/e
Publishing Year
2008
Pages
7
Author Affiliations
1. PGI, Chandigarh, Postgraduate Institute of Medical Sciences and Research (PGIMER), Chandigarh, India
Chapter keywords

Abstract

In congenitally corrected transposition of great arteries (c-TGA) there is atrioventricular and ventriculo arterial discordance known as double discordance. Right atrium (RA) connects to morphologic left ventricle (LV) and LA connects to morphologic right ventricle (RV). Aorta arises from morphologic RV and pulmonary artery arises from morphologic LV. Double discordance of atrioventricular and ventriculoarterial connections maintain normal circulation. The morphologic RV giving rise to aorta is exposed to systemic circulation. c-TGA is commonly associated with ventricular septal defect (VSD), pulmonary stenosis (PS), left AV valve abnormalities and conduction defects. Clinical manifestations depend upon these associated lesions. Infants with slow pulse and a systolic murmur over precordium the physician should think of c-TGA. ECG findings of left axis deviation, q in V1, V2, no q in V5-6 and varying degrees of AV block are very suggestive. Neither great arteries are border forming on X-ray chest. Acyanotic patient with increased pulmonary vascularity and concave pulmonary arterial shadow, one should think of c-TGA associated wit large VSD. Echo evidences of RA opening to morphologic LV, LA opening to morphologic RV and double circle appearance of great arteries (aorta anterior and left) are characteristic findings. Catheterization and angiography are essential because coronary artery anatomy should be well visualized before surgery.

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