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Chapter-04 Oxygen and Carbon Dioxide Transport

BOOK TITLE: Oxygen Therapy

Author
1. Singh Navneet
ISBN
9788184481976
DOI
10.5005/jp/books/10584_4
Edition
2/e
Publishing Year
2008
Pages
16
Author Affiliations
1. Postgraduate Institute of Medical Education and Research, Chandigarh, India, Postgraduate Institute of Medical Education and Research, Chandigarh, Postgraduate Institute of Medical Education and Research, Sector-12, Chandigarh 160 012, India, Postgraduate Institute of Medical Education and Research Chandigarh, India, Postgraduate Institute of Medical, Education and Research, Chandigarh, India, Postgraduate Institute of MedicalEducation and Research, Chandigarh, India
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Abstract

Most tissues do not have any mechanism to store oxygen and are thus dependent on the circulatory system for supply of oxygen. A series of steps characterize the process of oxygen transport from environmental air to the mitochondria of individual cells. These processes are either convective or diffusive in nature. Convective oxygen transport is an active process that occurs in the tracheobronchial tree and circulation. Diffusive transport is a passive process (determined by differences in oxygen concentration in various tissues) and occurs in the alveolar-capillary membrane as well as between tissue capillaries, interstitium and individual cells. The presence of hemoglobin in red blood cells allow the blood to transport 30-100 fold more oxygen than could be transported simply in the form of dissolved oxygen in blood. Tissue hypoxemia can result if anaerobic metabolism (and hence lactic acid production) starts occurring due to lack of oxygen from any cause. This chapter summarizes the physiology of oxygen and carbon dioxide transport.

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