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Chapter-12 The Practical Aspects of Cytogenetics in Hematological Malignancies

BOOK TITLE: Laboratory Techniques in Haematology

Author
1. PS Amare
ISBN
9788184482201
DOI
10.5005/jp/books/10438_12
Edition
1/e
Publishing Year
2008
Pages
18
Author Affiliations
1. Tata Memorial Hospital, Mumbai
Chapter keywords

Abstract

Recurring chromosomal abnormalities have played a major role in diagnosis and genetic classification and prognostication of hematological malignancies. This chapter describes in depth the role and method of conventional karyotyping from blood, lymph node and spleen biopsies. It also gives methodology for FISH in diagnosis of acute and chronic leukemias.

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