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Chapter-25 HIV Testing and Laboratory Monitoring of the Neonate

BOOK TITLE: Essentials of Management of Pregnancy in HIV-Infected Women: A Handbook for Obstetricians and Gynecologists

Author

1. Vashishtha Alok

ISBN

9788184483154

DOI

10.5005/jp/books/10456_25

Edition

1/e

Publishing Year

2008

Pages

Author Affiliations

1. Aids Research and Treatment (ART) Center, Nirmal Medical Foundation, S-43, Shivalik Nagar, Haridwar, Uttarakhand, India, Nirmal Medical Foundation, Hardwar, Uttaranchal, India, Haridwar, India, National AIDS Control Organization, New Delhi, India, Haridwar

Chapter keywords

Abstract

Abstract

HIV antibody testing (ELISA and Western blot analysis) is not useful in the early neonatal period, because of the transplacental transfer of maternal HIV IgG antibodies into fetal circulation. Definitive HIV testing for the infant and children less than 18 months of age should employ specific virologic assays, (HIV DNA PCR, or HIV RNA PCR), and a positive test should be confirmed with repeat testing.

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