Intramuscular stimulation is a great scientific technique which is based on anatomy (myotomes). The knowledge of myotomes is essential. It requires minimal instruments (only thin solid flexible needles). Simple OPD technique and excellent results makes this technique very popular. It can be used in variety of conditions. For many conditions IMS act as magic for the patients suffering from chronic musculoskeletal pain. Every pain physician must learn this technique to give patient a quality, cost effective and long lasting pain relief treatment. Musculoskeletal pain is radiculopathic pain involving segmental peripheral nerve supplying affected muscle. Diagnosis is mainly clinical. Diagnosis is by signs of neuropathy which are subtle but can be found if the clinician knows where to look, and what to look for. Unfortunately, all external forms of physical stimulation are passive, and when application is halted, stimulation ceases.