In our opinion stimulation guided pain mapping is a very useful technique in identifying the DRG/Nerve roots involved in carrying the nociceptive impulses which can help us target available treatments precisely. Pain is a subjective symptom and expression of pain for the same degree of nociceptive input can vary between individuals. The nerve roots involved in carrying the nociceptive impulses can be identified either by looking at the pain dermatomal maps or by injection of a small amount of local anesthetic along the nerve roots involved and assessing the patient’s response. There is always a possibility that the injected local anesthetic can soak adjacent nerve roots, which can confuse the issue. Stimulation guided stereotactic pain mapping allows us to identify precisely the nerve roots involved in carrying the nociceptive impulses and gives us an anatomical diagnosis of the nerve roots involved. This can help us to target the available treatments precisely.