The liver consists of stroma which includes capsule, septa, reticular connective tissue and parenchyma which includes hepatic lobules, sinusoids, and portal lobules which are surrounded by Glisson’s capsule. The concept of hepatic triad, portal lobule and liver acinus are given along with hand drawn diagram showing histology of liver. Functions of liver are provided which makes text more understandable. Gall Bladder consists of mucosa, submucosa, muscular coat, perivascular fibrous coat and serosa. The lining epithelium is very tall columnar (tallest in body). Physiological aspect and clinical aspect of the organ is also given. The pancreas consists of endocrine as well as exocrine part. It is made up of small lobules covered on outside by loose connective tissue covering which sends septa inside separating the lobules from each other and at the same time loosely holding the lobules. The lobules primarily contain large number of serous acinar glands called pancreatic acini along with their collecting duct system. The endocrine part of pancreas, i.e. the islet of Langerhans is a collection of various types of cells present as an irregular group and found scattered amongst the pancreatic acini. Functional aspect with clinical conditions associated is also given. Relevant photomicrographs are given in atlas provided at the beginning of book.