Injuries of the oral cavity may be caused by physical or chemical causes. Physical injuries may be iatrogenic, self inflicted, traumatic or occupational. The most important iatrogenic cause in the repair of tooth affected by dental caries or other developmental defects and restoration of missing tooth. Iatrogenic cause also includes x-ray radiation and laser radiation. Self induced or factitous injuries are due to overzealous oral hygiene practice caused by psychotic or neurotic condition or habitual. Traumatic causes include a fall, fight, road accidents and sport injuries. Although chemical injuries are caused by environmental elements such as toxic levels of chemicals in the water, air or consumables, the restorative materials used in the routine dental practice play an important role. This chapter discuss about fractures of teeth, physical injuries of the bone, physical injuries of soft tissue, clinical feature and treatment are in detailed.