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Chapter-29 Aspergilloma

BOOK TITLE: Manual of Respiratory Medicine

Author
1. Hira Harmanjit Singh
ISBN
9788184484366
DOI
10.5005/jp/books/10485_29
Edition
1/e
Publishing Year
2008
Pages
7
Author Affiliations
1. Maulana Azad Medical College, Lok Nayak and GB Pant Hospitals, New Delhi, India, Respiratory ICU and Sleep Centre, Maulana Azad Medical College and Associated LN and GB Pant Hospitals, New Delhi, Maulana Azad Medical College and Associated Hospitals, New Delhi, India, Maulana Azad Medical College and Associated Hospitals New Delhi, India
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Abstract

Although fungi have been recognized as important pathogens for the last century, they were for many years considered unusual and limited to certain endemic areas. As a result, the development of antifungal agents has lagged far behind that of antibacterial agents. The first important antifungal drug, amphotericin B (AmB), introduced in 1955, was the mainstay of therapy until the 1980s when the first generation of triazole antifungal agents, i.e. ketoconazole, fluconazole, and itraconazole was introduced. During the last two decades, the incidence of systemic fungal infections has increased dramatically, associated with the development of transplantation techniques, advances in chemotherapy, and the appearance of the AIDS epidemic.

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