JaypeeDigital | Diagnosis of Latent Tuberculosis Infection: Recent Advances and Future Directions

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Chapter-12 Diagnosis of Latent Tuberculosis Infection: Recent Advances and Future Directions

BOOK TITLE: Tuberculosis

Author

1. Pai Madhukar
2. Joshi Rajnish
3. Kalantri Shriprakash

ISBN

9788184485141

DOI

10.5005/jp/books/10992_12

Edition

2/e

Publishing Year

2009

Pages

Author Affiliations

1. McGill University, 1020 Pine Avenue West Montreal, Canada H3A1A2, Biostatistics and Occupational Health, McGill University, Pine Avenue West Montreal, Canada H3A1A2, McGill University 1020 Pine Ave West, Montreal, QC H3A IA2, Canada, McGill University, Montreal, Canada, McGill University; McGill International TB Center, Montreal, Quebec, Canada
2. Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, India
3. Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, India

Chapter keywords

Abstract

Abstract

In this chapter, the current approach to diagnosis of latent TB infection (LTBI) using tuberculin skin test (TST) is first presented. The biology and development of interferon-gamma release assays (IGRAs) is covered in detail. The commercially available IGRAs their laboratory characteristics and current international guidelines for their use are described in detail.

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