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Chapter-19 Autonomic Dysfunction in Parkinson's Disease

BOOK TITLE: Movement Disorders: A Clinical and Therapeutic Approach

Author
1. Das Bibhukalyani
ISBN
9788184485264
DOI
10.5005/jp/books/10538_19
Edition
1/e
Publishing Year
2009
Pages
14
Author Affiliations
1. Bangur Institute of Neurosciences and Psychiatry, Kolkata, India, Nil Ratan Sarkar (NRS) Medical College and Hospital, Kolkata, West Bengal, India, Institute of Neurosciences, Kolkata, West Bengal, India
Chapter keywords

Abstract

Autonomic dysfunction in PD has remained controversial. Sir James Parkinson in his first description of shaking palsy reported the association of motor features with symptoms suggesting the involvement of the autonomic nervous system. His description included clinical features such as orthostatic hypotension, seborrhea, excessive salivation and dysuria (Parkinson J). Yet, the clinical importance of autonomic dysfunction in PD has continued to be disputed, and the presence of prominent autonomic dysregulation is considered to be suggestive of disease with more widespread involvement of the CNS like multiple system atrophy, an important differential diagnosis of Parkinson disease. (Bannister et al).

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