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Chapter-31 Prenatal Diagnostic Procedures

BOOK TITLE: Operative Obstetrics and Gynecology

Author
1. Deka Deepika
2. Agarwal Nutan
ISBN
9788184485370
DOI
10.5005/jp/books/11088_31
Edition
1/e
Publishing Year
2009
Pages
7
Author Affiliations
1. All India Institute of Medical Sciences, New Delhi, New Delhi, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India; Genetic and Fetal Medicine Committee FOGSI, All India Instiute of Medical Sciences, New Delhi, India, All India Institute of Medical Science, New Delhi, Obstetrics and Gynecology AIIMS, New Delhi, AIIMS, New Delhi, AIIMS, New Delhi, India, New Delhi, India, AIIMS New Delhi-110029, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, All India Institute of Medical Sciences, New Delhi, India; Genetics and Fetal Medicine Committee (FOGSI)-(2007-2010), India, Perinatal Medicine Committee Association Obstetrics and Gynaecology of Delhi (AOGD), India, All India Institute of Medical Sciences, New Delhi, India, All India Institute of Medical Sciences, New Delhi, India, Genetics and Fetal Medicine Committee (FOGSI)-(2007-2010), India, Perinatal Medicine Committee Association Obstetrics and Gynaecology of Delhi (AOGD), India, All India Institute of Medical Sciences , New D
2. AIIMS New Delhi-110029, New Delhi, India, All India Institute of Medical Sciences, New Delhi, India, New Delhi
Chapter keywords
bleeding, amniotic fluid, visualization, Rh negative, anterior placenta, abdomen, immune hydropes, prenatal diagnosis, amniocentesis, reproductive decision

Abstract

This chapter discusses some prenatal diagnostic procedures in detail. Procedures discussed include chorionic villus sampling (CVS), amniocentesis, and cordocentesis. Prenatal diagnosis by CVS allows early diagnosis, hence earlier and safer abortion can be performed if fetus is found affected. Transcervical CVS is performed if placenta is located posteriorly in lower uterine part, as the abdominal approach may be difficult in such cases. Biochemical analysis of amniotic fluid permits test for fetal lung maturity, open neural tube defects, and assess for various viral and bacterial perinatal infections. Cordocentesis assists in chromosomal analysis, single gene defects, other hematological disorders like thrombocytopenia, and fetal blood gas analysis. in this process, higher fetal loss may be expected if it is performed for severe IUGR, non-immune hydrops, or structural anomalies compared to cordocentesis for confirmation of genetic diseases.

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