Cardiovascular System trumps all specialities when it comes to RHE of number of question asked in USMLE. Cardiac Artery Diseases have always ben darlings of Boards, but with changing healthcare dynamics, more and more emphasis is being given to Preventative Cardiology and it is one of the fields that really need to be focused on, specially for Step 3. Notable topics in this chapter include Aortic Dissection, Coarctation of Aorta, Coronary Artery Disease (CAD), Hypercholesterolemia, Peripheral Vascular Disease (PVD), Ischemic Heart Disease, Myocardial Infarction (MI), Unstable Angina, STEMI, NSTEMI, Congestive Heart Failure (CHF), Valvular heart Disease, Cardiomyopathy, Pericarditis, Rate and Rythm disturbances like AV Blocks, Arrythmias, Atrial Flutter, Atrial Fibrillation (AF), Ventricular Fibrillation, Torsades; Cardiac Pacing, Pregnancy and CVS dysfunction. High yield features in this chapter include LDL management, EKG changes according to region involved, Valvular disease differential, Cardiac pharmacology with indications, contraindications and adverse effects.