This chapter pertains to blood cell’s and product’s disorder. One would find many questions being tested from this chapter, especially the widely pervasive anemias, and the life threatening coagulopathies. One of the important diagnostic tools in blood disorder is the peripheral film and the various cells types and therefore you would find pictures showing various cell types, which are usually tested as pictorial questions. Notable topics in this chapter are Iron deficiency anemia, Thalassemia, Sideroblastic anemia, Anemia of Chronic disease, Megaloblastic anemia, B12/Folic acid deficiency anemia, Hemolytic anemia, Sickle cell disease, Hereditary Spherocytosis, G6PD deficiency, Autoimmune hemolytic anemias, Paroxysmal Nocturnal Hemoglobinuria, Idiopathic Thrombocytopenic Purprura (ITP), Thrombotic Thrombocytopenic Purpura (TTP), Hemolytic Uremic syndrome (HUS), von Willebrand disease, Hemophilia, Vitamin K deficiency, Disseminated Intravascular Coagulation (DIC), AML, ALL, CML, CLL, Polycythemia Vera, Aplastic anemia, Multiple myeloma, Monoclonal Gammopathy of Undetermined Significance (MGUS), Hodgkin Disease, Non-Hodgkin Lymphoma. Few of the quick reference tools in this chapter are Various RBC types, Characteristic RBC inclusions and associated diseases, Differential of Microcytic anemia, differentiation of Coagulopathy and platelet disorder.