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Chapter-06 Pathogenesis and Pathology of Diabetic Retinopathy

BOOK TITLE: Diabetic Retinopathy for the Clinician

Author
1. Biswas Jyotirmay
2. Das Arup
ISBN
9788184485554
DOI
10.5005/jp/books/10205_6
Edition
1/e
Publishing Year
2009
Pages
10
Author Affiliations
1. Sankara Nethralaya, Medical and Vision Research Foundation, Chennai, India, Sankara Nethralaya, Chennai, Tamil Nadu, India, Medical and Vision Research Foundation Sankara Nethralaya, 18, College Road Chennai, India, Medical and Vision Research Foundations, Chennai, Tamil Nadu, India, Medical and Vision Research Foundation, Shankara Nethralaya, Chennai, Sankara Nethralaya, Chennai, India, Medical Research Foundation, Sankara Nethralaya, Chennai, India, Sankara, Nethralaya, Chennai, Tamil Nadu, India, Sankara Nethralaya, A Unit of Medical Research Foundation, Nungambakkam, Chennai, Tamil Nadu, India, Sankara Nethralaya, Chennai, Tamil Nadu, Ind
2. University of New Mexico, Albuquerque, New Mexico, USA
Chapter keywords

Abstract

The aetiological factors dealt with in the previous chapter are recapitulated in the pathogenesis. The structural and functional changes in the blood retinal barrier, pericyte loss, capillary basement membrane thickening, loss of cellular elements from retinal capillaries, microaneurysm formation, retinal ischaemia, endothelial cell proliferation, retinal neovascularisation, and vitreous changes, are described. The different clinical lesions that constitute diabetic retinopathy are correlated with the histopathology findings.

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