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Chapter-18 Twilight Zone in High Grade Cervical Cytology (ASC-H, LSIL-H) and Future Trends in Cervical Cytology

BOOK TITLE: Cytology and Colposcopy in Gynecological Practice

Author
1. Shidham Vinod B
ISBN
9788184485844
DOI
10.5005/jp/books/10194_18
Edition
1/e
Publishing Year
2009
Pages
14
Author Affiliations
1. Cyto Journal http://www.cytojournal.com; Wisconsin Society of Pathologists; FNAB Service, and International Cytopathology Fellowship
Chapter keywords

Abstract

This discussion highlights the grey-zone of cytomorphologic spectrum which overlaps with high-grade squamous intraepithelial lesion (HSIL) in cervical cytology. Some cases in this spectrum may have to be interpreted as ‘atypical squamous cells, cannot exclude HSIL’ (ASC-H) or as ‘low-grade squamous intraepithelial lesion (LSIL) along with some features of ASC-H’ (LSIL-H). A brief description highlights future trends in this area in particular and cervical cytology in general. Extensively cited bibliography is additional resource for readers to explore in depth. Liquid Based Cytology is popularized in USA and in some developed countries and is said to give increased sensitivity and afford material for HPV Testing. However, well performed conventional Cytology is still the effective and economical tool for cancer detection. It has shown drastic reduction in incidence and mortality rates of cervical cancer when mass screening programmes are successfully conducted.

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