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Chapter-07 Sexual Dysfunction

BOOK TITLE: Drug Screening Methods: Preclinical Evaluation of New Drugs

Author
1. Mathur Rajani
2. Velpandian T
ISBN
9788184486186
DOI
10.5005/jp/books/10244_7
Edition
2/e
Publishing Year
2009
Pages
11
Author Affiliations
1. Delhi Institute of Pharmaceutical Sciences and Research (Delhi University), Pushp Vihar, New Delhi, Delhi Institute of Pharmaceutical Sciences and Research (DIPSAR), MB Road, Pushp Vihar, Sector-3, New Delhi (India), All India Institute of Medical Sciences, Ansari Nagar, New Delhi-110029, India, Delhi Institute of Pharmaceutical, Sciences and Research, Pushp Vihar, Sector-3, New Delhi, India, Delhi Institute of Pharmaceutical, Sciences and Research, Pushp Vihar Sector-3, New Delhi, India, Delhi Institute of Pharmaceutical Sciences and Research (DIPSAR), University of Delhi, New Delhi, India, Delhi Institute of Pharmaceutical Sciences and Research, University of Delhi, Pushp Vihar, Sector-3, New Delhi, India, Delhi Institute of Pharmaceutical Sciences and Research, New Delhi, India
2. Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029 (India), Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi-110029, India, Dr Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
Chapter keywords

Abstract

Sexual dysfunction is well recognized in both males and females. In vivo systems such as vasculogenic impotence, arteriogenic impotence, athesclerotic impotence, post-traumatic arteriogenic impotence, cavernous nerve injury, venous incompetence induced impotence, psychical erectile dysfunction, diabetes mellitus induced impotence are some important models that simulate pathophysiological basis of impotence in animals as seen in human males. Vaginal or clitoral smooth muscle preparation, pelvic nerve electrical stimulation are some of the screening models used to study female sexual dysfunction.

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