After myocardial infarction a number of intracellular proteins are released from damaged cells. They have diagnostic importance and are called cardiac markers. Diagnostically important cardiac markers includes creatine kinase, lactate dehydrogenase, aspartate aminotransferase, myoglobin and cardiac troponin T and I. Tests used to estimate increase risk of cardiovascular disease are lipid profile, C-reactive protein, homocysteine, and apolipoproteins. Lipid profile includes measurement of total serum cholesterol, HDL cholesterol, LDL cholesterol and serum triglycerides. In most studies apoA1 and apoB100 were somewhat better discriminator of those with coronary heart disease than were HDL and LDL cholesterol respectively. High value of Lp (a) is associated with increase risk of CHD.