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Chapter-02 Pathology and Pathogenesis

BOOK TITLE: Tuberculosis of the Skeletal System

Author

1. Tuli SM

ISBN

9788184488364

DOI

10.5005/jp/books/11046_2

Edition

4/e

Publishing Year

2010

Pages

Author Affiliations

1. Banaras Hindu University, Varanasi, India, University College of Medical Science and Guru Teg Bahadur Hospital, New Delhi, Delhi University College of Medical Sciences and GTB Hospital, New Delhi, India, Vidyasagar Institute of Mental Health and Neurosciences, Nehru Nagar, New Delhi, India, Vidyasagar Institute of Mental Health and Neurosciences, New Delhi, India, Vimhans PrimaMed Super Speciality Hospital, New Delhi, India, Vidyasagar Institute of Mental Health and Neurosciences, Nayati Medical Institutes, New Delhi, India, Vidyasagar Institute of Mental Health and Neurosciences, Vimhans Nayati Superspeciality Hospital, New Delhi, India

Chapter keywords

Abstract

Abstract

In the developing half of world almost all people get infected with mycobacterial organisms. Only about 3% show clinically manifest active disease. Development of osteoarticular TB is a slow process as compared to pulmonary TB. The involved bones undergo hyperemia, demineralization, softening, collapse and deformation. Most of the lesions develop cold abscess of variable sizes, and the abscess may present at a distance from the basic lesion. TB associated with implants and therapeutically refractory disease is a challenge to treatment.

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