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Chapter-10 Manganese Deficiency and Retina

BOOK TITLE: Nutrition and the Eye

Author
1. Pinelli Roberto
2. Elborgy Ebrahim
ISBN
9788184488623
DOI
10.5005/jp/books/11052_10
Edition
1/e
Publishing Year
2010
Pages
2
Author Affiliations
1. Istituto Laser Microchirurgia Oculare, Crystal Palace, Via Cefalonia, 70, 25124 Brescia, Italy, Istituto Laser Microchirurgia Oculare Crystal Palace, Via Cefalonia 70 25124, Brescia, Italy, European School for Advanced Studies in Ophthalmology (ESASO), Universitá della Svizzera Italiana, Lugano, Switzerland, Microchirurgia Oculare, Crystal Palace, Suite, Via Cefalonia, 70 25124 Brescia - Italy, Istituto Laser Microchirurgia Oculare, Crystal Palace, Via Cefalonia, 70, Brescia, Italy, Istituto Laser Microchirurgia Oculare, Crystal Palace, Via Cefalonia, Brescia, Italy, www.ilmo.it, Istituto Laser Microchirurgia Oculare, Crystal Palace, Via Cefalonia, Brescia, Italy, Instituto Laser Microchirurgia Oculare, Crystal Palace, Via Cefalonia, Brescia, Italy, Istituto Laser Microchirurgia Oculare, Crystal Palace, Via Cefalonia, 70, 25124, Brescia, Italy, Istituto Laser Microchirurgia, Oculare Crystal Palace, Via Cefalonia, 70, 25124, Brescia, Italy, Crystal Palace Via Cefalonia, 70 25124 Brescia, Italy, Istituto Laser
2. Research Institute of Ophthalmology, Giza, Egypt
Chapter keywords

Abstract

Manganese deficiency may disturb the renewal of photoreceptor outer segment discs and the decrease in antioxidant action caused by a lower level of Mn superoxide dismutase may accelerate the damage to photoreceptor cells. Manganese appears to be essential for maintaining photoreceptor cells. The retina has a high content of manganese: 31.8 fxgl/00 g wet tissue and 260/ig/100g dry tissue. Damage of the photoreceptor cells caused by manganese deficiency was specific probably because of mitochondria-rich and membrane-rich special structures. The increase of mitochondria in the retinal pigment epithelium may be die result of compensation for mitochondrial dysfunction caused by manganese deficiency.

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