Immunology of Ocular Allergy

by Manfred Zierhut, Tilo Biedermann, Santa Jeremy Ono

The aim of the presented book is to study the immunologic reactions of ocular allergy in comparison to allergic skin diseases. After an update about the epidemiology of ocular allergy and the role of environment in allergy, the clinic of dermal and ocular allergic disorders will be presented. On ocular side this includes vernal and atopic keratoconjunctivitis and the heyfever type of seasonal conjunctivitis. On dermal side this covers urticaria, idiopathic thrombocytopenic purpura, hypersensitivity vasculitis, contact dermatitis and atopic dermatitis. After these more general and clinical chapters, the immune cells, involved in allergic reactions, are presented. This includes detailed chapters about the major players in allergy, namely basophils, mast cells, B-cells, resulting in the production of dominating IgE, dendritic cells, T-cells and eosinophilic cells. Atopic keratoconjunctivitis is a possible blinding disorder, which often needs keratoplasty. Atopy as a risk factor for corneal transplantation is also covered in a separate chapter. The chapter, treatment strategies for ocular allergy will be presented. This includes chapters about mast cell stabilizing drugs, antihistamines, systemic immune therapy and immunomodulatory strategies, used for the most severe forms of ocular allergy. This book will update our knowledge about the pathophysiology of ocular allergy, besides summarizing our clinical knowledge and updated treatment strategies, keeping in touch with research from dermatology and allergy.

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Book Detail

Editor Editor's Affiliation
1. Zierhut Manfred
University of Tuebingen, Tuebingen, Germany
2. Biedermann Tilo
University of Tuebingen, Tuebingen, Germany
3. Ono Santa Jeremy Emory Univeristy Atlanta, Georgia, USA
ISBN 9788184488630
Speciality Ophthalmology
DOI 10.5005/jp/books/11118
Edition 1/e
Publishing Year 2010
Pages 264
Book Type Professional

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