This chapter discusses trabecular bypass surgery. Aqueous humor in human eyes is produced continuously in ciliary processes through ultrafiltration of blood and secretion of the filtered fluid. It enters the anterior chamber through the pupil and drains out through the angle structures at the periphery of the iris. This continuous production of aqueous humor provides nutrition of intraocular structures such as lens and cornea as well as stabilization of the eye with proper intraocular pressure. Experimental evidence has demonstrated that the trabecular meshwork is the site of increased outflow resistance in patients with open angle glaucoma. Recent theoretical work supported the concept of trabecular bypassing and dilatation of Schlemm’s canal. Surgical procedure is explained. Recent studies have confirmed safety and relatively good pressure lowering effect of trabecular bypass surgery with micro stent. This glaucoma procedure could be used safely in combination with phacoemulsification.