This chapter provides detail description of Cervical disc disease and spondylosis—Clinical features and diagnosis. Chapter has 8 well illustrated diagrams and pictures. Cervical spondylosis, distribution of sign and symptoms in nerve root lesions, cervical radiculopathy, imaging evaluation for cervical spondylosis and neurophysiologic studies, differential diagnosis are described in detail. 2 tables are included to highlight distributions of sign and symptoms of nerve root lesions and differential diagnosis. 16 references are included at the end of the chapter to facilitate further reading