This chapter provides detail description of Germ cell tumours of the central nervous system. Chapter has 2 well illustrated diagrams and pictures. Germ cell tumors of the central nervous system, clinical features and localization of germ cell tumors, imaging features of germ cell tumors, pathology of germ cell tumors, germinoma, teratoma, yolk sac tumor, embryonal carcinoma, histogenesis of germ cell tumors, prognostic and predictive factors are described in detail. 9 references are included at the end of the chapter to facilitate further reading.