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Chapter-077 Vasospasm and Its Management

BOOK TITLE: Ramamurthi and Tandon’s Textbook of Neurosurgery (3 Volumes)

Author
1. Pande Anil
2. Ramamurthi Ravi
ISBN
9789350250723
DOI
10.5005/jp/books/10307_77
Edition
3/e
Publishing Year
2012
Pages
33
Author Affiliations
1. Achanta Lakshmipathi Neurosurgical Center, VHS Hospitals, Chennai, Tamil Nadu, India, Postgraduate Institute of Neurological Surgery, Dr A Lakshmipathi Neurosurgical Centre, VHS Hospital, Chennai, Tamil Nadu, India
2. Achanta Lakshmipathi Neurosurgical Center, VHS Hospitals, Chennai, Tamil Nadu, India, Dr A Lakshmipathi Neurosurgical Centre, VHS Hospital, Chennai, Tamil Nadu, India, Postgraduate Institute of Neurological Surgery, Dr A Lakshmipathi Neurosurgical Centre, VHS Hospital, Chennai, Tamil Nadu, India, Dr Achanta Lakshmipathi Neurosurgical Centre, Postgraduate Institute of Neurological Surgery, Voluntary Health Services Hospital, Taramani, Chennai, Tamil Nadu, India
Chapter keywords

Abstract

This chapter provides detail description of Vasospasm and its management. Chapter has 6 well illustrated diagrams and pictures. Vasospasm, historical overview of vasospasm, chronology, risk factors for developing vasospasm, site of occurrence of vasospasm, classification and grading of vasospasm, experimental models for studying vasospasm, aetiopathogenesis of vasospasm, biology of cerebral blood vessels, genetics and pathophysiology of vasospasm at molecular level, red blood cells components and other spasmogens, vasculopathy, trauma of manipulation of arteries, hypothalamus, sympathetic plexus, apoptosis and vasospasm, cascade of events before and after vasospasm, early brain injury, clinical features of vasospasm, investigation related to vasospasm, cerebral blood flow studies, electroencephalography, transcranial Doppler, computerized tomography-angiography, single photon emission computed tomography, treatment of vasospasm, triple-H therapy, pharmacological prevention of vasospasm, free radical scavengers, recombinant tissue plasminogen activator, timing of surgery in relation to vasospasm, cerebrospinal fluid drainage, outcome of patients with vasospasm are described in detail. 305 references are included at the end of the chapter to facilitate further reading.

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