EXPORT CITATION

Chapter-25 Resistant Hepatitis B Virus Infection: Pathogenesis, Implications and Management

BOOK TITLE: Comprehensive Textbook of Hepatitis B

Author
1. Murali R
2. Saraswat Vivek A
ISBN
9789350250815
DOI
10.5005/jp/books/11250_25
Edition
1/e
Publishing Year
2011
Pages
18
Author Affiliations
1. Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
2. Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, U.P., India
Chapter keywords

Abstract

With the advent of nucleoside analogs, drug resistance has become a topic in the context of management of patients with chronic hepatitis B. Antiviral therapy with nucleoside analogs may induce resistant strain of HBV that is difficult to handle. It is now possible to diagnose HBV resistance. However, these patients should be properly followed up, a fact that can not be ascertained in most countries of the world that harbor majority of HBV-infected subjects. Resistant HBV may cause severe liver diseases and they are hard to control by antiviral drugs. Understanding of viral resistance is highly important to tackle these patients. It is important to design a management strategy of resistant patients in local perspectives. Mechanism of resistance and their management have been widely described in this chapter so that these can be helpful to clinicians.

© 2019 Jaypee Brothers Medical Publishers (P) LTD.   |   All Rights Reserved