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Chapter-42 Thyroid Dysfunction with Pregnancy

BOOK TITLE: A Comprehensive Textbook of Obstetrics & Gynecology

Author
1. Gupta Sadhana
ISBN
9789350251126
DOI
10.5005/jp/books/11278_41
Edition
1/e
Publishing Year
2011
Pages
4
Author Affiliations
1. Ultrasound, Infertility and In Vitro Fertilization (IVF) Specialist, Jeevan Jyoti Hospital, Gorakhpur, Uttar Pradesh, India, Gorakhpur, Uttar Pradesh, Bombay Hospital, Mumbai, Jeevan Jyoti Hospital and Medical Research Center and Jeevan Jyoti Test Tube Baby Center, Gorakhpur, UP, India, Jeevan Jyoti Hospital and Medical Research Center, Jeevan Jyoti Test Tube Baby Center, Gorakhpur, UP, India, Jeevan Jyoti Hospital and Medical Research Centre, Gorakhpur, Uttar Pradesh, India, FOGSI 2011–2013; Jeevan Jyoti Hospital and Medical Research Center, Gorakhpur, Uttar Pradesh, India, Jeevan Jyoti Hospital and Medical Research Center, Jeevan Jyoti Test Tube Baby Center, Gorakhpur, Uttar Pradesh, India, Jeevan-Jyoti Hospital, Gorakhpur, Uttar Pradesh, India, Jeevan Jyoti Hospital and Medical Research Centre, Gorakhpur, Uttar Pradesh, India; FOGSI 2016, Jeeevan Jyoti Hospital and Medical Research Centre, Gorakhpur, Uttar Pradesh, India, FOGSI, 2016, FOGSI Representative to SAFOG, 2018-20; Safe Motherhood Committee, FOG
Chapter keywords

Abstract

Untreated thyroid dysfunction can result in adverse maternal, fetal and neonatal sequelae. Physiology of maternal and fetal thyroid is summarized in the chapter followed by specific problem of hyper and hypothyroidism in pregnancy. Hyperthyroidism is mainly caused by Grave’s disease. High index of suspicion of hyperthyroidism, evaluation of serial thyroid function test, choice and dose adjustment of antithyroid drugs, and serial maternal, fetal and neonatal evaluation are important considerations, which are well covered in the chapter. Diagnosis of hypothyroidism by thyroid function test and treatment by thyroxine replacement are principle of management. Management of solitary thyroid nodule and postpartum thyroiditis is concised in the chapter.

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