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Chapter 12 Tropical Pulmonary Eosinophilia

BOOK TITLE: NCCP Textbook of Respiratory Medicine

Author
1. Vijayan VK
ISBN
9789350252123
DOI
10.5005/jp/books/11207_12
Edition
1/e
Publishing Year
2011
Pages
4
Author Affiliations
1. Vallabhbhai Patel Chest Institute, University of Delhi, P.O. Box No. 2101, Delhi, India, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India, Vallabhbhai Patel Chest Institute, University of Delhi, PO Box 2101, Delhi, India, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, VP Chest Institute, University of Delhi, New Delhi, India, VP Chest Institute, University of Delhi, Delhi, VP Chest Institute, University of Delhi, Delhi, India, VP Chest Institute University of Delhi, Delhi, India, Indian Council of Medical Research (ICMR), Bhopal Memorial Hospital and Research, Centre and National Institute for Research, in Environmental Health, Bhopal, Madhya Pradesh, India, Bhopal Memorial Hospital and Research Centre, National Institute for Research in Environmental Health, Bhopal, Madhya Pradesh, India, Indian Council of Medical Research, Bhopal Memorial Hospital and Research Centre, National Institute for Research in Environmental Health, Bhopal, Madhya Pradesh, India, National Institut
Chapter keywords

Abstract

Tropical pulmonary eosinophilia (TPE) is characterized by cough, dyspnea and nocturnal wheezing; diffuse reticulonodular infiltrates in chest X-rays and marked peripheral blood eosinophilia. The histopathological study in TPE had shown widely scattered nodules of varying sizes (1–5 mm) over the lung surface. The TPE is a systemic disease involving mainly the lungs, but other organs such as liver, spleen, lymph nodes, brain, gastrointestinal tract, etc. may also be involved. The efficacy of organic arsenicals in the treatment of TPE was reported by Weingarten. Because of persistent mild interstitial lung disease and high relapse rates in TPE, it has been recommended that repeated monthly courses of diethylcarbamazine citrate (DEC) at 2-3 monthly intervals for a period of 1-2 years may be useful.

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