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Chapter 17 Bronchial Asthma

BOOK TITLE: NCCP Textbook of Respiratory Medicine

Author
1. Shah Ashok
2. Sareen Richa
3. Motiani PD
4. Singh Sheetu
ISBN
9789350252123
DOI
10.5005/jp/books/11207_17
Edition
1/e
Publishing Year
2011
Pages
74
Author Affiliations
1. Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India, Vallabhbhai Patel Chest Institute, University of Delhi, PO Box 2101, Delhi, India, Grant Medical College and Sir JJ Group of Hospitals; Harkisandas Hospital Breach Candy Hospital, Mumbai, Maharashtra, India, VP Chest Institute, University of Delhi, PO Box 2101, New Delhi, India, VP Chest Institute, University of Delhi, P.O. Box 2101, Delhi, Harkisondas Hospital, Breach Candy Hospital, Mumbai, India, VP Chest Institute, University of Delhi, Delhi, India, Peel Health Campus, Mandurah, WA, Australia, Vallabhbhai Patel Chest Institute, New Delhi, India, Vallabhbhai Patel Chest Institute, University of Delhi, New Delhi, India
2. Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India
3. KN Chest Hospital, SN Medical College, Jodhpur, Rajasthan, India
4. SMS Medical College, Jaipur, Rajasthan, India
Chapter keywords

Abstract

The problem of asthma is increasing worldwide and the developing nations are now being affected due to rapid and extensive industrialization along with haphazard urbanization. The exponential research done in the fields of immunology, pathophysiology, molecular and cell biology in the recent decades suggests interplay between host, genetic and environmental factors in the pathogenesis of asthma. Allergic bronchopulmonary aspergillosis should be considered in any patient with asthma and pulmonary infiltrates. Gastroesophageal reflux disease is a clinically important cause of respiratory disorders. Bronchial asthma (BA) predisposes patients to GERD, whereas GERD may induce or aggravate BA. Despite the conflicting evidence coming on in recent years, it is still appropriate to treat moderate to severe persistent asthma with symptoms of GERD with proton pump inhibitors (PPI) to achieve better control. However, although the prevalence of asymptomatic GERD is high in asthmatics, no recommendation can be made to treat all asthmatics with PPIs for achieving better control.

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