Postoperative jaundice is given in detail. Bilirubin overproduction, hypoxic liver injury, effect of surgery and anesthesia on liver flow, jaundice after cardiac surgery, intraoperative and all other postoperative factors causing postoperative jaundice, clinical features, diagnosis and management of postoperative jaundice are described in detail. A flow chart is included to highlight algorithm for diagnosis of postoperative jaundice. 8 references are given at the end of the chapter to facilitate further reading.