This chapter provides detail description of FNAC in round cell tumor. Chapter has 4 well illustrated diagrams and pictures. Fine needle aspiration in small round cell tumor, cytomorphology, neuroblastoma, Ewing’s sarcoma and peripheral neuroectodermal tumor, Wilm’s tumor, rhabdomyosarcoma, desmoplastic small round cell tumor are described in detail with the help of excellent illustrations and histopathological pictures. All salient features of different lesions are highlighted in 3 boxes. 2 tables are included to provide details of cytomorphology of small round cell tumor and immunocytochemistry of small round cell tumor for easy learning. 6 references are included at the end of the chapter to facilitate further reading.