This chapter provides detail description of Vitamin E. Chapter has 2 well-illustrated diagrams and pictures. Biochemistry and metabolism of vitamin E, sources, requirement, functions of vitamin E, epidemiology, vitamin E deficiency, haemolytic anaemia, antioxidant actions, vitamin E and haemolytic anaemia, vitamin E and immune system function, evaluation of vitamin E status, toxicity, oral vitamin therapy are given in detail. 2 tables are included to highlight details of tocopherol and vitamin E content of vegetable oils. 13 references are given at the end of the chapter for further reading.