This chapter provides detail description of medical history in dentistry. Medical history, check list for medical history by Scully and Cawson, family history is described in detail. Check list for medical history highlight anaemia, bleeding disorders, cardiovascular disease, respiratory disease, endocrine disorder, fits and faint, gastrointestinal disorders, hospital admission and surgeries. One box is included to depict Scully and Cawson check list for medical history.