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Chapter-15 Principles of Plaque Radiation Therapy

BOOK TITLE: Retinoblastoma

Author

1. Ramasubramanian Aparna
2. Shields Carol L
3. Mukherjee Archana

ISBN

9789350257845

DOI

10.5005/jp/books/11629_15

Edition

1/e

Publishing Year

2012

Pages

Author Affiliations

1. Eugene and Marilyn Glick Eye Institute, Indiana University School of Medicine, Indianapolis, Indiana, USA, Moran Eye Center, University of Utah, Salt Lake City, Utah, USA, University of Louisville Louisville, Kentucky-40202, USA
2. Wills Eye Institute, Philadelphia, Pennsylvania, USA, Wills Eye Hospital, Philadelphia, USA, Wills Eye Institute, Thomas Jefferson University, Philadelphia, PA, U.S.A
3. Bhabha Atomic Research Centre, Trombay, Mumbai, Maharashtra, India

Chapter keywords

Abstract

Abstract

Retinoblastoma is a radiosensitive tumor and the first use of brachytherapy for retinoblastoma was reported in 1929 by Foster Moore. In this chapter authors discuss the radiation principles involved with plaque therapy. Plaque radiotherapy is a useful adjuvant method to treat localized retinoblastoma tumor and recurrence. Careful plaque configuration and placement is critical for success of the treatment and to limit the radiation effects to normal tissues. A number of radioisotopes have been reported for plaque radiotherapy. Iodine-125 and Ruthenium-106 are the most commonly used sources.

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