This chapter provides detail description of Management of multifetal pregnancy. Multifetal pregnancy, Pre-pregnancy prevention, antenatal management, delivery considerations, caesarean section, twin reverse arterial perfusion syndrome, twin to twin transfusion syndrome, monoamniotic gestation, discordant twins, locked twins, intrauterine death of one fetus and do’s and don\'ts in multifetal pregnancy are described in detail. 1 table is added to highlight do\'s and don\'ts in multifetal gestation. 10 references are included at the end of the chapter to facilitate further reading.