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Chapter-24 E Epidermal Noncultured Cell Suspension in Vitiligo

BOOK TITLE: ACS(I) Textbook on Cutaneous and Aesthetic Surgery

Author
1. Paul Munish
ISBN
9789350258903
DOI
10.5005/jp/books/11651_29
Edition
1/e
Publishing Year
2012
Pages
6
Author Affiliations
1. Skin Laser Centre 235, Avtar Enclave, Paschim Vihar, New Delhi, India, Skin Laser Center, New Delhi, India, Skin Laser Centre, New Delhi, India
Chapter keywords

Abstract

As discussed in earlier chapters, medical treatments are not successful in all cases of vitiligo. Tissue grafts have the limitations that large amount of donor skin is needed as there is no cell expansion in these methods. Hence, transplantation of autologous cultured and noncultured melanocytes which involve cell suspension without culture or keratinocyte/melanocyte cocultures are gaining popularity. Transplantation of noncultured melanocytes/keratinocytes suspension has the advantage that cell culture is not needed and that skin harvesting from the donor area, cell separation and application of melanocytes can all be undertaken in a single 3 hour procedure. Indications, contraindications, case selection, preoperative investigations have all been dealt in earlier chapters. This chapter will deal therefore only with specific details of the procedure.

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